The Little Snake River Valley has long been used to cross over the Sierra Madre Mountains and Continental Divide between the Green River and Platte River drainages. The Native Americans learned to follow the existing migratory bison trails, which later became immigrant routes and modern day roads. As a result, the valley was often host to the Sioux, Arapahoe, Cheyenne, Shoshoni, Ute and Crow tribes, many of whom did not get along, but were able to manage a mutual sharing of local travel and resources. Their presence is evidenced by campsites where tipi rings and lithic debris from flintknapping can be found. Some of the stone points retrieved in the area date back over 10,000 years and some can be seen at the Little Snake River Museum.